NIKOLAOS VLAHOS
Professor for Obstetrics and Gynecology and Assisted Reproduction
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New publications and presentations from our team. Updates on recent scientific meetings congresses and developments.
Myomas and Adenomyosis: Impact on Reproductive Outcome
Among uterine structural abnormalities, myomas and adenomyosis represent two distinct, though frequently coexistent entities, with a remarkable prevalence in women of reproductive age. Various mechanisms have been proposed to explain the impact of each of them on reproductive outcome. In respect to myomas, current evidence implies that submucosal ones have an adverse effect on conception and early pregnancy. A similar effect yet is not quite clear and has been suggested for intramural myomas. Still, it seems reasonable that intramural myomas greater than 4 cm in diameter may negatively impair reproductive outcome. On the contrary, subserosal myomas do not seem to have a signifcant impact, if any, on reproduction. Te presence of submucosal and/or large intramural myomas has also been linked to adverse pregnancy outcomes. In particular increased risk for miscarriage, fetal malpresentation, placenta previa, preterm birth, placenta abruption, postpartum hemorrhage, and cesarean section has been reported. With regard to adenomyosis, besides the tentative coexistence of adenomyosis and infertility, to date a causal relationship among these conditions has not been fully confrmed. Preterm birth and preterm premature rupture of membranes, uterine rupture, postpartum hemorrhage due to uterine atony, and ectopic pregnancy have all been reported in association with adenomyosis. Further research on the impact of adenomyosis on reproductive outcome is welcome.
Fertility drugs and ovarian cancer risk: a critical review of the literature
ANNALS OF THE NEW YORK ACADEMY OF SCIENCES Issue: Women’s Health and Disease Nikos F. Vlahos,1,2 Konstantinos P. Economopoulos,1,3 and George Creatsas1 1Second Department of Obstetrics and Gynecology, Aretaieio Hospital, University of Athens, School of Medicine, Athens, Greece. 2Department of Gynecology and Obstetrics, Johns Hopkins University School of Medicine, Baltimore, Maryland. 3Society of Junior Doctors, Athens, Greece Address for correspondence: Nikos F. Vlahos, M.D., Second Department of Obstetrics and Gynecology, Aretaieio University Hospital, 76 Vas. Sofias Av., 11527, Athens, Greece. office2888@gmail.com
Endometriosis, in vitro fertilisation and the risk of gynaecological malignancies, including ovarian and breast cancer.
Endometriosis, in vitro fertilisation and the risk of gynaecological malignancies, including ovarian and breast cancer Nikos F. Vlahos, MD, Assistant Professor 1, Konstantinos P. Economopoulos, MD, Fellow Researcher *, Stylianos Fotiou, MD, Associate Professor 1 Department of Obstetrics and Gynecology, Aretaieio Hospital, University of Athens, 76 Vas. Sofias Av., 11527, Athens, Greece
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